Cargando…

Acute Toxoplasma Gondii Infection in Cats Induced Tissue-Specific Transcriptional Response Dominated by Immune Signatures

RNA-sequencing was used to detect transcriptional changes in six tissues of cats, seven days after T. gondii infection. A total of 737 genes were differentially expressed (DEGs), of which 410 were up-regulated and 327 were down-regulated. The liver exhibited 151 DEGs, lung (149 DEGs), small intestin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cong, Wei, Dottorini, Tania, Khan, Faraz, Emes, Richard D., Zhang, Fu-Kai, Zhou, Chun-Xue, He, Jun-Jun, Zhang, Xiao-Xuan, Elsheikha, Hany M., Zhu, Xing-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202952/ https://www.ncbi.nlm.nih.gov/pubmed/30405608 http://dx.doi.org/10.3389/fimmu.2018.02403

Ejemplares similares

Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection
por: Cong, Wei, et al.
Publicado: (2017)

Transcriptomic insights into the early host-pathogen interaction of cat intestine with Toxoplasma gondii
por: Wang, Meng, et al.
Publicado: (2018)

Transcriptional changes in Toxoplasma gondii in response to treatment with monensin
por: Zhai, Bintao, et al.
Publicado: (2020)

Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection
por: Ma, Jun, et al.
Publicado: (2019)

Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures
por: Wang, Ze-Xiang, et al.
Publicado: (2019)

Proteomic Profiling of Mouse Liver following Acute Toxoplasma gondii Infection
por: He, Jun-Jun, et al.
Publicado: (2016)

Global Transcriptome Profiling of Multiple Porcine Organs Reveals Toxoplasma gondii-Induced Transcriptional Landscapes
por: He, Jun-Jun, et al.
Publicado: (2019)

Seroprevalence of Toxoplasma gondii infection in arthritis patients in eastern China
por: Tian, Ai-Ling, et al.
Publicado: (2017)

Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts
por: Hu, Rui-Si, et al.
Publicado: (2020)

Acetylome analysis of the feline small intestine following Toxoplasma gondii infection
por: Meng, Yu-Meng, et al.
Publicado: (2020)

ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell
por: Li, Jie-Xi, et al.
Publicado: (2020)

Differential Brain MicroRNA Expression Profiles After Acute and Chronic Infection of Mice With Toxoplasma gondii Oocysts
por: Hu, Rui-Si, et al.
Publicado: (2018)

Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
por: Nie, Lan-Bi, et al.
Publicado: (2020)

Transcriptome Profiling of Toxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin
por: Harun, Mohammad S. R., et al.
Publicado: (2020)

Dual Identification and Analysis of Differentially Expressed Transcripts of Porcine PK-15 Cells and Toxoplasma gondii during in vitro Infection
por: Zhou, Chun-Xue, et al.
Publicado: (2016)

Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection
por: He, Jun-Jun, et al.
Publicado: (2016)

Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry
por: Zhou, Chun-Xue, et al.
Publicado: (2018)

Dynamic RNA profiles in the small intestinal epithelia of cats after Toxoplasma gondii infection
por: Zhai, Bintao, et al.
Publicado: (2023)

Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry-Based Metabolomics Reveals Metabolic Alterations in the Mouse Cerebellum During Toxoplasma gondii Infection
por: Ma, Jun, et al.
Publicado: (2020)

iTRAQ-based Quantitative Proteomics Analysis Identifies Host Pathways Modulated during Toxoplasma gondii Infection in Swine
por: He, Jun-Jun, et al.
Publicado: (2020)

Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds
por: Nie, Lan-Bi, et al.
Publicado: (2022)

Functional Characterization of Rhoptry Kinome in the Virulent Toxoplasma gondii RH Strain
por: Wang, Jin-Lei, et al.
Publicado: (2017)

Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
por: Zhou, Chun-Xue, et al.
Publicado: (2015)

Comparative proteomic analysis of virulent and avirulent strains of Toxoplasma gondii reveals strain-specific patterns
por: Zhou, Dong-Hui, et al.
Publicado: (2017)

Identification of host proteins interacting with Toxoplasma gondii GRA15 (TgGRA15) by yeast two-hybrid system
por: Liu, Qing, et al.
Publicado: (2017)

Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice
por: Li, Zhong-Yuan, et al.
Publicado: (2018)

Immunization with Toxoplasma gondii GRA17 Deletion Mutant Induces Partial Protection and Survival in Challenged Mice
por: Wang, Jin-Lei, et al.
Publicado: (2017)

Proteomic Differences between Developmental Stages of Toxoplasma gondii Revealed by iTRAQ-Based Quantitative Proteomics
por: Wang, Ze-Xiang, et al.
Publicado: (2017)

iTRAQ-Based Global Phosphoproteomics Reveals Novel Molecular Differences Between Toxoplasma gondii Strains of Different Genotypes
por: Wang, Ze-Xiang, et al.
Publicado: (2019)

Prevalence of antibodies against Toxoplasma gondii in pets and their owners in Shandong province, Eastern China
por: Cong, Wei, et al.
Publicado: (2018)

Global proteomic profiling of multiple organs of cats (Felis catus) and proteome-transcriptome correlation during acute Toxoplasma gondii infection
por: Nie, Lan-Bi, et al.
Publicado: (2022)

Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors
por: Zhu, Yu-Chao, et al.
Publicado: (2021)

The protein phosphatase 2A holoenzyme is a key regulator of starch metabolism and bradyzoite differentiation in Toxoplasma gondii
por: Wang, Jin-Lei, et al.
Publicado: (2022)

Functional Characterization of Dense Granule Proteins in Toxoplasma gondii RH Strain Using CRISPR-Cas9 System
por: Bai, Meng-Jie, et al.
Publicado: (2018)

THE TOXOPLASMA GONDII OOCYST FROM CAT FECES
por: Dubey, J. P., et al.
Publicado: (1970)

Toxoplasma gondii seroprevalence varies by cat breed
por: Must, Kärt, et al.
Publicado: (2017)

Seroprevalence of Toxoplasma gondii in Cats from Cyprus
por: Attipa, Charalampos, et al.
Publicado: (2021)

Toxoplasma gondii spinal granuloma in a cat
por: Tyroller, Florian, et al.
Publicado: (2023)

Prevalence of Toxoplasma gondii in Dogs in Zhanjiang, Southern China
por: Jiang, Hai-Hai, et al.
Publicado: (2015)

Seroprevalence of Toxoplasma gondii infection in household and stray cats in Lanzhou, northwest China
por: Wu, Song-Ming, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_li743jupjph9lcg4e1b14imapi