Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma

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Polygodial, a drimane sesquiterpenoid dialdehyde isolated as a pungent component of the water pepper Persicaria hydropiper, exhibits antifeedant, antimicrobial, anti-inflammatory and anticancer effects. Polygodial also activates transient receptor potential vanilloid subtype 1 (TRPV1) channels. Prev...

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Detalles Bibliográficos
Autores principales: De La Chapa, Jorge, Singha, Prajjal Kanti, Sallaway, Mckay, Self, Kristen, Nasreldin, Ranna, Dasari, Ramesh, Hart, Matthew, Kornienko, Alexander, Just, Jeremy, Smith, Jason a., Bissember, Alex C., Gonzales, Cara b.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203145/
https://www.ncbi.nlm.nih.gov/pubmed/30320372
http://dx.doi.org/10.3892/ijo.2018.4585
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