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Overexpression of Gremlin 1 by sonic hedgehog signaling promotes pancreatic cancer progression

Sonic hedgehog (SHH) signaling is an important promotor of desmoplasia, a critical feature in pancreatic cancer stromal reactions involving the activation of pancreatic stellate cells (PSCs). Gremlin 1 is widely overexpressed in cancer-associated stromal cells, including activated PSCs. In embryonic...

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Detalles Bibliográficos
Autores principales:	Yu, Yongtian, Cheng, Liang, Yan, Bin, Zhou, Cancan, Qian, Weikun, Xiao, Ying, Qin, Tao, Cao, Junyu, Han, Liang, Ma, Qingyong, Ma, Jiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203161/ https://www.ncbi.nlm.nih.gov/pubmed/30272371 http://dx.doi.org/10.3892/ijo.2018.4573

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