Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1(rd8) Allele

PURPOSE: To determine the molecular basis of lesion development in a murine model of spontaneous retinal vascularization, rnv3 (retinal vascularization 3, aka JR5558). METHODS: Disease progression of rnv3 was examined in longitudinal studies by clinical evaluation, electroretinography (ERG) and ligh...

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Detalles Bibliográficos
Autores principales: Chang, Bo, FitzMaurice, Bernard, Wang, Jieping, Low, Benjamin E., Wiles, Michael V., Nishina, Patsy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203173/
https://www.ncbi.nlm.nih.gov/pubmed/30372741
http://dx.doi.org/10.1167/iovs.18-25046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203173/
https://www.ncbi.nlm.nih.gov/pubmed/30372741
http://dx.doi.org/10.1167/iovs.18-25046

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