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Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1(rd8) Allele
PURPOSE: To determine the molecular basis of lesion development in a murine model of spontaneous retinal vascularization, rnv3 (retinal vascularization 3, aka JR5558). METHODS: Disease progression of rnv3 was examined in longitudinal studies by clinical evaluation, electroretinography (ERG) and ligh...
Autores principales: | Chang, Bo, FitzMaurice, Bernard, Wang, Jieping, Low, Benjamin E., Wiles, Michael V., Nishina, Patsy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203173/ https://www.ncbi.nlm.nih.gov/pubmed/30372741 http://dx.doi.org/10.1167/iovs.18-25046 |
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