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Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R
[Image: see text] Carbohydrate moieties are essential for the biological activity of anthracycline anticancer agents such as nogalamycin, which contains l-nogalose and l-nogalamine units. The former of these is attached through a canonical O-glycosidic linkage, but the latter is connected via an unu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203184/ https://www.ncbi.nlm.nih.gov/pubmed/30114358 http://dx.doi.org/10.1021/acschembio.8b00658 |