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Synthesis of Azide-Modified Chondroitin Sulfate Precursors: Substrates for “Click”- Conjugation with Fluorescent Labels and Oligonucleotides
[Image: see text] Azidopropyl-modified precursors of chondroitin sulfate (CS) tetrasaccharides have been synthesized, which, after facile conversion to final CS structures, may be conjugated with alkyne-modified target compounds by a one-pot “click”-ligation. RP HPLC was used for the monitoring of t...
Autores principales: | Jadhav, Satish, Gulumkar, Vijay, Deshpande, Prasannakumar, Coffey, Eleanor T., Lönnberg, Harri, Virta, Pasi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203187/ https://www.ncbi.nlm.nih.gov/pubmed/29856920 http://dx.doi.org/10.1021/acs.bioconjchem.8b00317 |
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