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A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report

BACKGROUND: The involvement of granulomatosis with polyangiitis is less frequent in the intestine. CASE PRESENTATION: We present a case of Wegener’s granulomatosis with unusual endoscopic appearance, involvement in a young man’s gastrointestinal tract. A 45-year-old man was diagnosed with Wegener’s...

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Autores principales: Pan, Sheng-Wu, Wang, Chang, Zhang, Xin, Zhang, Li, Yan, Qi-Qi, Zhao, Cai-Juan, Chang, Cheng, Luan, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203215/
https://www.ncbi.nlm.nih.gov/pubmed/30359222
http://dx.doi.org/10.1186/s12876-018-0885-9
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author Pan, Sheng-Wu
Wang, Chang
Zhang, Xin
Zhang, Li
Yan, Qi-Qi
Zhao, Cai-Juan
Chang, Cheng
Luan, Xiao-Dong
author_facet Pan, Sheng-Wu
Wang, Chang
Zhang, Xin
Zhang, Li
Yan, Qi-Qi
Zhao, Cai-Juan
Chang, Cheng
Luan, Xiao-Dong
author_sort Pan, Sheng-Wu
collection PubMed
description BACKGROUND: The involvement of granulomatosis with polyangiitis is less frequent in the intestine. CASE PRESENTATION: We present a case of Wegener’s granulomatosis with unusual endoscopic appearance, involvement in a young man’s gastrointestinal tract. A 45-year-old man was diagnosed with Wegener’s granulomatosis 11 years ago, and relapsed with abdominal pain and melena. A colonoscopy was performed, and the appearance of mucosal lesions with an unusual annular black membrane was observed. A black ring-shaped membranous tissue adhered to the surface of the colon wall, which could be traversed by an endoscopic forepart. CONCLUSION: Biopsy of the black membrane revealed degenerative colonic mucosal tissues, while deep colonic biopsy revealed inflammatory granulation tissues. This has not been reported in previous documents.
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spelling pubmed-62032152018-11-01 A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report Pan, Sheng-Wu Wang, Chang Zhang, Xin Zhang, Li Yan, Qi-Qi Zhao, Cai-Juan Chang, Cheng Luan, Xiao-Dong BMC Gastroenterol Case Report BACKGROUND: The involvement of granulomatosis with polyangiitis is less frequent in the intestine. CASE PRESENTATION: We present a case of Wegener’s granulomatosis with unusual endoscopic appearance, involvement in a young man’s gastrointestinal tract. A 45-year-old man was diagnosed with Wegener’s granulomatosis 11 years ago, and relapsed with abdominal pain and melena. A colonoscopy was performed, and the appearance of mucosal lesions with an unusual annular black membrane was observed. A black ring-shaped membranous tissue adhered to the surface of the colon wall, which could be traversed by an endoscopic forepart. CONCLUSION: Biopsy of the black membrane revealed degenerative colonic mucosal tissues, while deep colonic biopsy revealed inflammatory granulation tissues. This has not been reported in previous documents. BioMed Central 2018-10-25 /pmc/articles/PMC6203215/ /pubmed/30359222 http://dx.doi.org/10.1186/s12876-018-0885-9 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Pan, Sheng-Wu
Wang, Chang
Zhang, Xin
Zhang, Li
Yan, Qi-Qi
Zhao, Cai-Juan
Chang, Cheng
Luan, Xiao-Dong
A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title_full A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title_fullStr A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title_full_unstemmed A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title_short A rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
title_sort rare endoscopic appearance of granulomatosis with polyangiitis involving the intestine: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203215/
https://www.ncbi.nlm.nih.gov/pubmed/30359222
http://dx.doi.org/10.1186/s12876-018-0885-9
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