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An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells

Genetically encoded calcium indicator (GCaMP) proteins have been reported for imaging cardiac cell activity based on intracellular calcium transients. To bring human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) to the clinic, it is critical to evaluate the functionality of CMs. Here, we...

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Detalles Bibliográficos
Autores principales:	Jiang, Yuqian, Zhou, Yuxiao, Bao, Xiaoping, Chen, Chuanxin, Randolph, Lauren N., Du, Jing, Lian, Xiaojun Lance
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203247/ https://www.ncbi.nlm.nih.gov/pubmed/30368079 http://dx.doi.org/10.1016/j.isci.2018.10.007

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