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Canonical and single-cell Hi-C reveal distinct chromatin interaction sub-networks of mammalian transcription factors

BACKGROUND: Transcription factor (TF) binding to regulatory DNA sites is a key determinant of cell identity within multi-cellular organisms and has been studied extensively in relation to site affinity and chromatin modifications. There has been a strong focus on the inference of TF-gene regulatory...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyan, Ezer, Daphne, Adryan, Boris, Stevens, Tim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203279/
https://www.ncbi.nlm.nih.gov/pubmed/30359306
http://dx.doi.org/10.1186/s13059-018-1558-2