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Induction of CD4(+)CD25(+)FOXP3(+) regulatory T cells by mesenchymal stem cells is associated with modulation of ubiquitination factors and TSDR demethylation

BACKGROUND: Mesenchymal stem cells (MSCs) are known for their ability to induce the conversion of conventional T cells (Tconvs) into induced regulatory T cells (iTregs) in specific inflammatory contexts. Stable Foxp3 expression plays a major role in the phenotypic and functional stability of iTregs....

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Detalles Bibliográficos
Autores principales:	Khosravi, Maryam, Bidmeshkipour, Ali, Cohen, José L., Moravej, Ali, Hojjat-Assari, Suzzan, Naserian, Sina, Karimi, Mohammad Hossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203284/ https://www.ncbi.nlm.nih.gov/pubmed/30359308 http://dx.doi.org/10.1186/s13287-018-0991-1

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