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Modeling three-dimensional invasive solid tumor growth in heterogeneous microenvironment under chemotherapy
A systematic understanding of the evolution and growth dynamics of invasive solid tumors in response to different chemotherapy strategies is crucial for the development of individually optimized oncotherapy. Here, we develop a hybrid three-dimensional (3D) computational model that integrates pharmac...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203364/ https://www.ncbi.nlm.nih.gov/pubmed/30365511 http://dx.doi.org/10.1371/journal.pone.0206292 |