Cargando…

Therapeutic effects of favipiravir against severe fever with thrombocytopenia syndrome virus infection in a lethal mouse model: Dose-efficacy studies upon oral administration

Severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), is a viral hemorrhagic fever with a high case fatality rate. Favipiravir was reported to be effective in the treatment of SFTSV infection in vivo in type I interferon receptor knockout (IFNAR(−/−)) mice at treatment do...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tani, Hideki, Komeno, Takashi, Fukuma, Aiko, Fukushi, Shuetsu, Taniguchi, Satoshi, Shimojima, Masayuki, Uda, Akihiko, Morikawa, Shigeru, Nakajima, Nozomi, Furuta, Yousuke, Saijo, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203377/ https://www.ncbi.nlm.nih.gov/pubmed/30365543 http://dx.doi.org/10.1371/journal.pone.0206416

Ejemplares similares

Efficacy of T-705 (Favipiravir) in the Treatment of Infections with Lethal Severe Fever with Thrombocytopenia Syndrome Virus
por: Tani, Hideki, et al.
Publicado: (2016)

Combination effects of ribavirin and interferons on severe fever with thrombocytopenia syndrome virus infection
por: Shimojima, Masayuki, et al.
Publicado: (2015)

Favipiravir treatment prolongs the survival in a lethal mouse model intracerebrally inoculated with Jamestown Canyon virus
por: Kato, Hirofumi, et al.
Publicado: (2021)

Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV
por: Fujii, Hikaru, et al.
Publicado: (2022)

Inability of rat DPP4 to allow MERS-CoV infection revealed by using a VSV pseudotype bearing truncated MERS-CoV spike protein
por: Fukuma, Aiko, et al.
Publicado: (2015)

Serologic assays for the detection and strain identification of Pteropine orthoreovirus
por: Singh, Harpal, et al.
Publicado: (2016)

Rapid whole genome sequencing of Miyazaki-Bali/2007 Pteropine orthoreovirus by modified rolling circular amplification with adaptor ligation – next generation sequencing
por: Singh, Harpal, et al.
Publicado: (2015)

M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening
por: Yamada, Hiroshi, et al.
Publicado: (2021)

Analysis of the Function of the Lymphocytic Choriomeningitis Virus S Segment Untranslated Region on Growth Capacity In Vitro and on Virulence In Vivo
por: Taniguchi, Satoshi, et al.
Publicado: (2020)

Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers
por: Fukushi, Shuetsu, et al.
Publicado: (2012)

Severe Fever with Thrombocytopenia Syndrome Virus Antigen Detection Using Monoclonal Antibodies to the Nucleocapsid Protein
por: Fukuma, Aiko, et al.
Publicado: (2016)

Severe Fever with Thrombocytopenia Syndrome Phlebovirus causes lethal viral hemorrhagic fever in cats
por: Park, Eun-sil, et al.
Publicado: (2019)

Family Cluster Analysis of Severe Fever with Thrombocytopenia Syndrome Virus Infection in Korea
por: Yoo, Jeong Rae, et al.
Publicado: (2016)

Phosphorylation of p38 MAPK and its downstream targets in SARS coronavirus-infected cells
por: Mizutani, Tetsuya, et al.
Publicado: (2004)

Importance of Akt signaling pathway for apoptosis in SARS-CoV-infected Vero E6 cells
por: Mizutani, Tetsuya, et al.
Publicado: (2004)

Regulation of p90RSK phosphorylation by SARS‐CoV infection in Vero E6 cells
por: Mizutani, Tetsuya, et al.
Publicado: (2006)

Characterization of Persistent SARS-CoV Infection in Vero E6 Cells
por: Mizutani, Tetsuya, et al.
Publicado: (2006)

JNK and PI3k/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells
por: Mizutani, Tetsuya, et al.
Publicado: (2005)

Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase
por: FURUTA, Yousuke, et al.
Publicado: (2017)

Effective inactivation of Nipah virus in serum samples for safe processing in low-containment laboratories
por: Watanabe, Shumpei, et al.
Publicado: (2020)

Analysis of the entry mechanism of Crimean-Congo hemorrhagic fever virus, using a vesicular stomatitis virus pseudotyping system
por: Suda, Yuto, et al.
Publicado: (2016)

Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophylaxis
por: Yamada, Kentaro, et al.
Publicado: (2016)

A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome
por: Yoshikawa, Tomoki, et al.
Publicado: (2021)

Virulence, pathology, and pathogenesis of Pteropine orthoreovirus (PRV) in BALB/c mice: Development of an animal infection model for PRV
por: Egawa, Kazutaka, et al.
Publicado: (2017)

Pseudotyped Vesicular Stomatitis Virus for Functional Analysis of Sars Coronavirus Spike Protein
por: Fukushi, Shuetsu, et al.
Publicado: (2006)

Tyrosine dephosphorylation of STAT3 in SARS coronavirus‐infected Vero E6 cells
por: Mizutani, Tetsuya, et al.
Publicado: (2004)

Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents
por: Ikejiri, Masahiro, et al.
Publicado: (2007)

Characterization of novel monoclonal antibodies against the MERS-coronavirus spike protein and their application in species-independent antibody detection by competitive ELISA
por: Fukushi, Shuetsu, et al.
Publicado: (2018)

Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus
por: Saijo, Masayuki, et al.
Publicado: (2005)

The broad-spectrum antiviral favipiravir protects guinea pigs from lethal Lassa virus infection post-disease onset
por: Safronetz, David, et al.
Publicado: (2015)

Diagnostic system for the detection of severe fever with thrombocytopenia syndrome virus RNA from suspected infected animals
por: Park, Eun-sil, et al.
Publicado: (2021)

Severe Fever with Thrombocytopenia Syndrome, Japan, 2013–2017
por: Kobayashi, Yusuke, et al.
Publicado: (2020)

A multicenter non-randomized, uncontrolled single arm trial for evaluation of the efficacy and the safety of the treatment with favipiravir for patients with severe fever with thrombocytopenia syndrome
por: Suemori, Koichiro, et al.
Publicado: (2021)

Efficient functional screening of a cellular cDNA library to identify severe fever with thrombocytopenia syndrome virus entry factors
por: Shimojima, Masayuki, et al.
Publicado: (2020)

Mechanisms of establishment of persistent SARS-CoV-infected cells
por: Mizutani, Tetsuya, et al.
Publicado: (2006)

Favipiravir (T-705) protects against Nipah virus infection in the hamster model
por: Dawes, Brian E., et al.
Publicado: (2018)

Use of Favipiravir to Treat Lassa Virus Infection in Macaques
por: Rosenke, Kyle, et al.
Publicado: (2018)

Ligation-mediated amplification for effective rapid determination of viral RNA sequences (RDV)
por: Watanabe, Shumpei, et al.
Publicado: (2008)

Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines
por: Taniguchi, Satoshi, et al.
Publicado: (2012)

Pathological Characteristics of a Patient with Severe Fever with Thrombocytopenia Syndrome (SFTS) Infected with SFTS Virus through a Sick Cat’s Bite
por: Tsuru, Masatoshi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mhifkknek3f634a1vlm4sttlrm