Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription

Alterations in global mRNA decay broadly impact multiple stages of gene expression, although signals that connect these processes are incompletely defined. Here, we used tandem mass tag labeling coupled with mass spectrometry to reveal that changing the mRNA decay landscape, as frequently occurs dur...

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Detalles Bibliográficos
Autores principales: Gilbertson, Sarah, Federspiel, Joel D, Hartenian, Ella, Cristea, Ileana M, Glaunsinger, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203436/
https://www.ncbi.nlm.nih.gov/pubmed/30281021
http://dx.doi.org/10.7554/eLife.37663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203436/
https://www.ncbi.nlm.nih.gov/pubmed/30281021
http://dx.doi.org/10.7554/eLife.37663

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