Cargando…
Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription
Alterations in global mRNA decay broadly impact multiple stages of gene expression, although signals that connect these processes are incompletely defined. Here, we used tandem mass tag labeling coupled with mass spectrometry to reveal that changing the mRNA decay landscape, as frequently occurs dur...
Autores principales: | Gilbertson, Sarah, Federspiel, Joel D, Hartenian, Ella, Cristea, Ileana M, Glaunsinger, Britt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203436/ https://www.ncbi.nlm.nih.gov/pubmed/30281021 http://dx.doi.org/10.7554/eLife.37663 |
Ejemplares similares
-
RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters
por: Hartenian, Ella, et al.
Publicado: (2020) -
Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis
por: Duncan-Lewis, Christopher, et al.
Publicado: (2021) -
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability
por: Vijjamarri, Anil Kumar, et al.
Publicado: (2023) -
Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
por: Chan, Leon Y, et al.
Publicado: (2018) -
sRNA-mediated activation of gene expression by inhibition of 5'-3’ exonucleolytic mRNA degradation
por: Durand, Sylvain, et al.
Publicado: (2017)