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Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O

The lytic capacity of cholesterol-dependent cytolysins is enhanced in the extracellular calcium-free environment through a combination of limited membrane repair and diminished membrane toxin removal. For a typical neurotoxin of the group, pneumolysin, this effect has already been observed at reduce...

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Detalles Bibliográficos
Autores principales: Maurer, Jana, Hupp, Sabrina, Pillich, Helena, Mitchell, Timothy J., Chakraborty, Trinad, Iliev, Asparouh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203718/
https://www.ncbi.nlm.nih.gov/pubmed/30367146
http://dx.doi.org/10.1038/s41598-018-34031-4

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