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Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O
The lytic capacity of cholesterol-dependent cytolysins is enhanced in the extracellular calcium-free environment through a combination of limited membrane repair and diminished membrane toxin removal. For a typical neurotoxin of the group, pneumolysin, this effect has already been observed at reduce...
Autores principales: | Maurer, Jana, Hupp, Sabrina, Pillich, Helena, Mitchell, Timothy J., Chakraborty, Trinad, Iliev, Asparouh I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203718/ https://www.ncbi.nlm.nih.gov/pubmed/30367146 http://dx.doi.org/10.1038/s41598-018-34031-4 |
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