Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate

Chronic myelomonocytic leukemia (CMML) is an entity of myelodysplastic syndrome/myeloproliferative neoplasm. Although CMML can be cured with allogeneic stem cell transplantation, its prognosis is generally very poor due to the limited efficacy of chemotherapy and to the patient’s age, which is usual...

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Detalles Bibliográficos
Autores principales: Taoka, Kazuki, Arai, Shunya, Kataoka, Keisuke, Hosoi, Masataka, Miyauchi, Masashi, Yamazaki, Sho, Honda, Akira, Aixinjueluo, Wei, Kobayashi, Takashi, Kumano, Keiki, Yoshimi, Akihide, Otsu, Makoto, Niwa, Akira, Nakahata, Tatsutoshi, Nakauchi, Hiromitsu, Kurokawa, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203784/
https://www.ncbi.nlm.nih.gov/pubmed/30367142
http://dx.doi.org/10.1038/s41598-018-34193-1

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