A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

BACKGROUND: Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associated with clinical and in vitro resistance phenotypes; however, several studi...

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Detalles Bibliográficos
Autores principales: Breglio, Kimberly F., Amato, Roberto, Eastman, Richard, Lim, Pharath, Sa, Juliana M., Guha, Rajarshi, Ganesan, Sundar, Dorward, David W., Klumpp-Thomas, Carleen, McKnight, Crystal, Fairhurst, Rick M., Roberts, David, Thomas, Craig, Simon, Anna Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204056/
https://www.ncbi.nlm.nih.gov/pubmed/30367653
http://dx.doi.org/10.1186/s12936-018-2532-x

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