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CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging

The past two decades have witnessed rapid and remarkable technical improvement of multidetector computed tomography (CT) in both image quality and diagnostic accuracy. These improvements include higher temporal resolution, high-definition and wider detectors, the introduction of dual-source and dual...

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Autores principales: Seitun, Sara, De Lorenzi, Cecilia, Cademartiri, Filippo, Buscaglia, Angelo, Travaglio, Nicole, Balbi, Manrico, Bezante, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204157/
https://www.ncbi.nlm.nih.gov/pubmed/30406139
http://dx.doi.org/10.1155/2018/7295460
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author Seitun, Sara
De Lorenzi, Cecilia
Cademartiri, Filippo
Buscaglia, Angelo
Travaglio, Nicole
Balbi, Manrico
Bezante, Gian Paolo
author_facet Seitun, Sara
De Lorenzi, Cecilia
Cademartiri, Filippo
Buscaglia, Angelo
Travaglio, Nicole
Balbi, Manrico
Bezante, Gian Paolo
author_sort Seitun, Sara
collection PubMed
description The past two decades have witnessed rapid and remarkable technical improvement of multidetector computed tomography (CT) in both image quality and diagnostic accuracy. These improvements include higher temporal resolution, high-definition and wider detectors, the introduction of dual-source and dual-energy scanners, and advanced postprocessing. Current new generation multidetector row (≥64 slices) CT systems allow an accurate and reliable assessment of both coronary epicardial stenosis and myocardial CT perfusion (CTP) imaging at rest and during pharmacologic stress in the same examination. This novel application makes CT the unique noninvasive “one-stop-shop” method for a comprehensive assessment of both anatomical coronary atherosclerosis and its physiological consequences. Myocardial CTP imaging can be performed with different approaches such as static arterial first-pass imaging, and dynamic CTP imaging, with their own advantages and disadvantages. Static CTP can be performed using single-energy or dual-energy CT, employing qualitative or semiquantitative analysis. In addition, dynamic CTP can obtain quantitative data of myocardial blood flow and coronary flow reserve. The purpose of this review was to summarize all available evidence about the emerging role of myocardial CTP to identify ischemia-associated lesions, focusing on technical considerations, clinical applications, strengths, limitations, and the more promising future fields of interest in the broad spectra of ischemic heart disease.
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spelling pubmed-62041572018-11-07 CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging Seitun, Sara De Lorenzi, Cecilia Cademartiri, Filippo Buscaglia, Angelo Travaglio, Nicole Balbi, Manrico Bezante, Gian Paolo Biomed Res Int Review Article The past two decades have witnessed rapid and remarkable technical improvement of multidetector computed tomography (CT) in both image quality and diagnostic accuracy. These improvements include higher temporal resolution, high-definition and wider detectors, the introduction of dual-source and dual-energy scanners, and advanced postprocessing. Current new generation multidetector row (≥64 slices) CT systems allow an accurate and reliable assessment of both coronary epicardial stenosis and myocardial CT perfusion (CTP) imaging at rest and during pharmacologic stress in the same examination. This novel application makes CT the unique noninvasive “one-stop-shop” method for a comprehensive assessment of both anatomical coronary atherosclerosis and its physiological consequences. Myocardial CTP imaging can be performed with different approaches such as static arterial first-pass imaging, and dynamic CTP imaging, with their own advantages and disadvantages. Static CTP can be performed using single-energy or dual-energy CT, employing qualitative or semiquantitative analysis. In addition, dynamic CTP can obtain quantitative data of myocardial blood flow and coronary flow reserve. The purpose of this review was to summarize all available evidence about the emerging role of myocardial CTP to identify ischemia-associated lesions, focusing on technical considerations, clinical applications, strengths, limitations, and the more promising future fields of interest in the broad spectra of ischemic heart disease. Hindawi 2018-10-14 /pmc/articles/PMC6204157/ /pubmed/30406139 http://dx.doi.org/10.1155/2018/7295460 Text en Copyright © 2018 Sara Seitun et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Seitun, Sara
De Lorenzi, Cecilia
Cademartiri, Filippo
Buscaglia, Angelo
Travaglio, Nicole
Balbi, Manrico
Bezante, Gian Paolo
CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title_full CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title_fullStr CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title_full_unstemmed CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title_short CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging
title_sort ct myocardial perfusion imaging: a new frontier in cardiac imaging
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204157/
https://www.ncbi.nlm.nih.gov/pubmed/30406139
http://dx.doi.org/10.1155/2018/7295460
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