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Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets

The previous study in our team found that supplementation of probiotic Bacillus amyloliquefaciens (Ba) instead of antibiotics promote growth performance of piglets. Hence, the present study was carried out to further demonstrate the effect of Ba replacement of antibiotics on digestive and absorption...

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Autores principales: Hu, Shenglan, Cao, Xuefang, Wu, Yanping, Mei, Xiaoqiang, Xu, Han, Wang, Yang, Zhang, Xiaoping, Gong, Li, Li, Weifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204369/
https://www.ncbi.nlm.nih.gov/pubmed/30405544
http://dx.doi.org/10.3389/fmicb.2018.02427
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author Hu, Shenglan
Cao, Xuefang
Wu, Yanping
Mei, Xiaoqiang
Xu, Han
Wang, Yang
Zhang, Xiaoping
Gong, Li
Li, Weifen
author_facet Hu, Shenglan
Cao, Xuefang
Wu, Yanping
Mei, Xiaoqiang
Xu, Han
Wang, Yang
Zhang, Xiaoping
Gong, Li
Li, Weifen
author_sort Hu, Shenglan
collection PubMed
description The previous study in our team found that supplementation of probiotic Bacillus amyloliquefaciens (Ba) instead of antibiotics promote growth performance of piglets. Hence, the present study was carried out to further demonstrate the effect of Ba replacement of antibiotics on digestive and absorption enzyme activity and intestinal microbiota population of piglets. A total of 90 piglets were selected and divided into three groups: G1 group was fed with basal diet supplemented with 150 mg/Kg aureomycin, G2 group was fed with 1 × 10(8) cfu/Kg Ba and half dose of aureomycin, G3 group was used the diet with 2 × 10(8)cfu/Kg Ba replaced aureomycin. Each treatment had three replications of 10 pigs per pen. Results indicated that Ba replacement significantly increased the activities of amylase, disaccharides and Na(+)/K(+)-ATPase. And chymotrypsin activity in different section of intestine was dramatically enhanced in half replacement of aureomycin with Ba. Moreover, Ba replacement maintained the intestinal integrity with the significantly decreased activity of DAO compared with aureomycin group. Besides, supplementation with Ba increased the β-diversity of intestinal microbiota. Taken together, the current study indicated that diet supplementation with Ba instead of aureomycin increased the growth performance of piglets by improving the digestive and absorb enzyme activities, enhancing the intestinal integrity and regulating the population of intestinal micrbiota.
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spelling pubmed-62043692018-11-07 Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets Hu, Shenglan Cao, Xuefang Wu, Yanping Mei, Xiaoqiang Xu, Han Wang, Yang Zhang, Xiaoping Gong, Li Li, Weifen Front Microbiol Microbiology The previous study in our team found that supplementation of probiotic Bacillus amyloliquefaciens (Ba) instead of antibiotics promote growth performance of piglets. Hence, the present study was carried out to further demonstrate the effect of Ba replacement of antibiotics on digestive and absorption enzyme activity and intestinal microbiota population of piglets. A total of 90 piglets were selected and divided into three groups: G1 group was fed with basal diet supplemented with 150 mg/Kg aureomycin, G2 group was fed with 1 × 10(8) cfu/Kg Ba and half dose of aureomycin, G3 group was used the diet with 2 × 10(8)cfu/Kg Ba replaced aureomycin. Each treatment had three replications of 10 pigs per pen. Results indicated that Ba replacement significantly increased the activities of amylase, disaccharides and Na(+)/K(+)-ATPase. And chymotrypsin activity in different section of intestine was dramatically enhanced in half replacement of aureomycin with Ba. Moreover, Ba replacement maintained the intestinal integrity with the significantly decreased activity of DAO compared with aureomycin group. Besides, supplementation with Ba increased the β-diversity of intestinal microbiota. Taken together, the current study indicated that diet supplementation with Ba instead of aureomycin increased the growth performance of piglets by improving the digestive and absorb enzyme activities, enhancing the intestinal integrity and regulating the population of intestinal micrbiota. Frontiers Media S.A. 2018-10-22 /pmc/articles/PMC6204369/ /pubmed/30405544 http://dx.doi.org/10.3389/fmicb.2018.02427 Text en Copyright © 2018 Hu, Cao, Wu, Mei, Xu, Wang, Zhang, Gong and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Hu, Shenglan
Cao, Xuefang
Wu, Yanping
Mei, Xiaoqiang
Xu, Han
Wang, Yang
Zhang, Xiaoping
Gong, Li
Li, Weifen
Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title_full Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title_fullStr Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title_full_unstemmed Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title_short Effects of Probiotic Bacillus as an Alternative of Antibiotics on Digestive Enzymes Activity and Intestinal Integrity of Piglets
title_sort effects of probiotic bacillus as an alternative of antibiotics on digestive enzymes activity and intestinal integrity of piglets
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204369/
https://www.ncbi.nlm.nih.gov/pubmed/30405544
http://dx.doi.org/10.3389/fmicb.2018.02427
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