Cargando…
Shining New Light on the Structural Determinants of Cardiac Couplon Function: Insights From Ten Years of Nanoscale Microscopy
Remodelling of the membranes and protein clustering patterns during the pathogenesis of cardiomyopathies has renewed the interest in spatial visualisation of these structures in cardiomyocytes. Coincidental emergence of single molecule (super-resolution) imaging and tomographic electron microscopy t...
Autores principales: | Jayasinghe, Izzy, Clowsley, Alexander H., de Langen, Oscar, Sali, Sonali S., Crossman, David J., Soeller, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204384/ https://www.ncbi.nlm.nih.gov/pubmed/30405432 http://dx.doi.org/10.3389/fphys.2018.01472 |
Ejemplares similares
-
Revealing T-Tubules in Striated Muscle with New Optical Super-Resolution Microscopy Techniquess
por: Jayasinghe, Isuru D., et al.
Publicado: (2014) -
Nanoscale Organisation of Ryanodine Receptors and Junctophilin-2 in the Failing Human Heart
por: Hou, Yufeng, et al.
Publicado: (2021) -
True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors
por: Jayasinghe, Izzy, et al.
Publicado: (2018) -
Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons
por: Dries, Eef, et al.
Publicado: (2018) -
Three-Dimensional
and Chemical Mapping of Intracellular
Signaling Nanodomains in Health and Disease with Enhanced Expansion
Microscopy
por: Sheard, Thomas M. D., et al.
Publicado: (2019)