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Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes

We analyzed T cell subsets from cryopreserved PBMC obtained from the TrialNet Pathway to Prevention archives. We compared subjects who had previously seroconverted for one or more autoantibodies with non-seroconverted, autoantibody negative individuals. We observed a reduced frequency of MAIT cells...

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Detalles Bibliográficos
Autores principales:	Harms, Robert Z., Lorenzo-Arteaga, Kristina M., Ostlund, Katie R., Smith, Victoria B., Smith, Lynette M., Gottlieb, Peter, Sarvetnick, Nora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204396/ https://www.ncbi.nlm.nih.gov/pubmed/30405601 http://dx.doi.org/10.3389/fimmu.2018.02332

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