Cargando…
DNMT3B Functions: Novel Insights From Human Disease
DNA methylation plays important roles in gene expression regulation and chromatin structure. Its proper establishment and maintenance are essential for mammalian development and cellular differentiation. DNMT3B is the major de novo DNA methyltransferase expressed and active during the early stage of...
Autores principales: | Gagliardi, Miriam, Strazzullo, Maria, Matarazzo, Maria R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204409/ https://www.ncbi.nlm.nih.gov/pubmed/30406101 http://dx.doi.org/10.3389/fcell.2018.00140 |
Ejemplares similares
-
Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction
por: Toubiana, Shir, et al.
Publicado: (2019) -
A Novel Dnmt3a1 Transcript Inhibits Adipogenesis
por: Abdalla, Bahareldin A., et al.
Publicado: (2018) -
The aberrant epigenome of DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory
por: Poondi Krishnan, Varsha, et al.
Publicado: (2023) -
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing
por: Gatto, Sole, et al.
Publicado: (2017) -
Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
por: Van Emburgh, Beth O., et al.
Publicado: (2011)