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Therapeutic Targeting Cancer-Initiating Cell Markers by Exosome miRNA: Efficacy and Functional Consequences Exemplified for claudin7 and EpCAM()
AIM: Transfer of exosomes (Exo) miRNA was described interfering with tumor progression. We here explored for claudin7 (cld7) and EpCAM (EpC), cancer-initiating-cell markers in colorectal and pancreatic cancer, the efficacy of Exo loading with miRNA and miRNA transfer. METHODS: Exo were collected fro...
Autores principales: | Kyuno, Daisuke, Zhao, Kun, Bauer, Nathalie, Ryschich, Eduard, Zöller, Margot |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204435/ https://www.ncbi.nlm.nih.gov/pubmed/30393102 http://dx.doi.org/10.1016/j.tranon.2018.08.021 |
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