Cargando…
LY2495655, an antimyostatin antibody, in pancreatic cancer: a randomized, phase 2 trial
BACKGROUND: Cachexia is a formidable clinical challenge in pancreatic cancer. We assessed LY2495655 (antimyostatin antibody) plus standard‐of‐care chemotherapy in pancreatic cancer using cachexia status as a stratifier. METHODS: In this randomized, phase 2 trial, patients with stage II–IV pancreatic...
Autores principales: | Golan, Talia, Geva, Ravit, Richards, Donald, Madhusudan, Srinivasan, Lin, Boris Kin, Wang, Haofei Tiffany, Walgren, Richard A., Stemmer, Salomon M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204586/ https://www.ncbi.nlm.nih.gov/pubmed/30051975 http://dx.doi.org/10.1002/jcsm.12331 |
Ejemplares similares
-
Antimyostatin Treatment in Health and Disease: The Story of Great Expectations and Limited Success
por: Nielsen, Tue L., et al.
Publicado: (2021) -
Molecular Profiling-Selected Therapy for Treatment of Advanced Pancreaticobiliary Cancer: A Retrospective Multicenter Study
por: Epelbaum, Ron, et al.
Publicado: (2015) -
A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients
por: Laquente, Berta, et al.
Publicado: (2017) -
Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies
Publicado: (1986) -
Efficacy and safety of abemaciclib alone and with PI3K/mTOR inhibitor LY3023414 or galunisertib versus chemotherapy in previously treated metastatic pancreatic adenocarcinoma: A randomized controlled trial
por: Chiorean, E. Gabriela, et al.
Publicado: (2023)