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Titin‐based mechanosensing modulates muscle hypertrophy

BACKGROUND: Titin is an elastic sarcomeric filament that has been proposed to play a key role in mechanosensing and trophicity of muscle. However, evidence for this proposal is scarce due to the lack of appropriate experimental models to directly test the role of titin in mechanosensing. METHODS: We...

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Detalles Bibliográficos
Autores principales: van der Pijl, Robbert, Strom, Joshua, Conijn, Stefan, Lindqvist, Johan, Labeit, Siegfried, Granzier, Henk, Ottenheijm, Coen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204599/
https://www.ncbi.nlm.nih.gov/pubmed/29978560
http://dx.doi.org/10.1002/jcsm.12319