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Oesophageal adenocarcinoma following gastric band surgery in two patients
Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204719/ https://www.ncbi.nlm.nih.gov/pubmed/30386553 http://dx.doi.org/10.1093/jscr/rjy293 |
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author | Lam, James Jie Min Di Maggio, Francesco Lynn, William Khoo, David |
author_facet | Lam, James Jie Min Di Maggio, Francesco Lynn, William Khoo, David |
author_sort | Lam, James Jie Min |
collection | PubMed |
description | Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit for a substantial population is huge. Although no causal relationship with bariatric procedures has been evidenced to date, symptoms of adenocarcinoma—particularly anorexia, weight loss and dysphagia—can easily be overshadowed by alterations in eating patterns associated with weight-loss procedures. We report two cases of oesophageal adenocarcinoma in patients who had undergone a gastric banding procedure, and invite readers to consider the role that pre- and post-operative acid reflux dynamics may have precipitating neoplastic disease, and how endoscopic surveillance may play a role in prevention. |
format | Online Article Text |
id | pubmed-6204719 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-62047192018-10-31 Oesophageal adenocarcinoma following gastric band surgery in two patients Lam, James Jie Min Di Maggio, Francesco Lynn, William Khoo, David J Surg Case Rep Case Report Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit for a substantial population is huge. Although no causal relationship with bariatric procedures has been evidenced to date, symptoms of adenocarcinoma—particularly anorexia, weight loss and dysphagia—can easily be overshadowed by alterations in eating patterns associated with weight-loss procedures. We report two cases of oesophageal adenocarcinoma in patients who had undergone a gastric banding procedure, and invite readers to consider the role that pre- and post-operative acid reflux dynamics may have precipitating neoplastic disease, and how endoscopic surveillance may play a role in prevention. Oxford University Press 2018-10-29 /pmc/articles/PMC6204719/ /pubmed/30386553 http://dx.doi.org/10.1093/jscr/rjy293 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Lam, James Jie Min Di Maggio, Francesco Lynn, William Khoo, David Oesophageal adenocarcinoma following gastric band surgery in two patients |
title | Oesophageal adenocarcinoma following gastric band surgery in two patients |
title_full | Oesophageal adenocarcinoma following gastric band surgery in two patients |
title_fullStr | Oesophageal adenocarcinoma following gastric band surgery in two patients |
title_full_unstemmed | Oesophageal adenocarcinoma following gastric band surgery in two patients |
title_short | Oesophageal adenocarcinoma following gastric band surgery in two patients |
title_sort | oesophageal adenocarcinoma following gastric band surgery in two patients |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204719/ https://www.ncbi.nlm.nih.gov/pubmed/30386553 http://dx.doi.org/10.1093/jscr/rjy293 |
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