Cargando…

Oesophageal adenocarcinoma following gastric band surgery in two patients

Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit...

Descripción completa

Detalles Bibliográficos
Autores principales: Lam, James Jie Min, Di Maggio, Francesco, Lynn, William, Khoo, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204719/
https://www.ncbi.nlm.nih.gov/pubmed/30386553
http://dx.doi.org/10.1093/jscr/rjy293
_version_ 1783366082275311616
author Lam, James Jie Min
Di Maggio, Francesco
Lynn, William
Khoo, David
author_facet Lam, James Jie Min
Di Maggio, Francesco
Lynn, William
Khoo, David
author_sort Lam, James Jie Min
collection PubMed
description Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit for a substantial population is huge. Although no causal relationship with bariatric procedures has been evidenced to date, symptoms of adenocarcinoma—particularly anorexia, weight loss and dysphagia—can easily be overshadowed by alterations in eating patterns associated with weight-loss procedures. We report two cases of oesophageal adenocarcinoma in patients who had undergone a gastric banding procedure, and invite readers to consider the role that pre- and post-operative acid reflux dynamics may have precipitating neoplastic disease, and how endoscopic surveillance may play a role in prevention.
format Online
Article
Text
id pubmed-6204719
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-62047192018-10-31 Oesophageal adenocarcinoma following gastric band surgery in two patients Lam, James Jie Min Di Maggio, Francesco Lynn, William Khoo, David J Surg Case Rep Case Report Oesophageal adenocarcinoma following gastric band surgery has only been reported three times previously. The incidence is higher in morbidly obese patients, and its pathogenesis is correlated to reflux-induced microenvironmental changes. Bariatric surgery is transformative and its potential benefit for a substantial population is huge. Although no causal relationship with bariatric procedures has been evidenced to date, symptoms of adenocarcinoma—particularly anorexia, weight loss and dysphagia—can easily be overshadowed by alterations in eating patterns associated with weight-loss procedures. We report two cases of oesophageal adenocarcinoma in patients who had undergone a gastric banding procedure, and invite readers to consider the role that pre- and post-operative acid reflux dynamics may have precipitating neoplastic disease, and how endoscopic surveillance may play a role in prevention. Oxford University Press 2018-10-29 /pmc/articles/PMC6204719/ /pubmed/30386553 http://dx.doi.org/10.1093/jscr/rjy293 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Lam, James Jie Min
Di Maggio, Francesco
Lynn, William
Khoo, David
Oesophageal adenocarcinoma following gastric band surgery in two patients
title Oesophageal adenocarcinoma following gastric band surgery in two patients
title_full Oesophageal adenocarcinoma following gastric band surgery in two patients
title_fullStr Oesophageal adenocarcinoma following gastric band surgery in two patients
title_full_unstemmed Oesophageal adenocarcinoma following gastric band surgery in two patients
title_short Oesophageal adenocarcinoma following gastric band surgery in two patients
title_sort oesophageal adenocarcinoma following gastric band surgery in two patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204719/
https://www.ncbi.nlm.nih.gov/pubmed/30386553
http://dx.doi.org/10.1093/jscr/rjy293
work_keys_str_mv AT lamjamesjiemin oesophagealadenocarcinomafollowinggastricbandsurgeryintwopatients
AT dimaggiofrancesco oesophagealadenocarcinomafollowinggastricbandsurgeryintwopatients
AT lynnwilliam oesophagealadenocarcinomafollowinggastricbandsurgeryintwopatients
AT khoodavid oesophagealadenocarcinomafollowinggastricbandsurgeryintwopatients