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Lipid A Remodeling Is a Pathoadaptive Mechanism That Impacts Lipopolysaccharide Recognition and Intracellular Survival of Burkholderia pseudomallei

Burkholderia pseudomallei causes the severe disease melioidosis. The bacterium subverts the host immune system and replicates inside cells, and host mortality results primarily from sepsis-related complications. Lipopolysaccharide (LPS) is a major virulence factor and mediator of sepsis that many pa...

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Detalles Bibliográficos
Autores principales: Norris, Michael H., Somprasong, Nawarat, Schweizer, Herbert P., Tuanyok, Apichai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204721/
https://www.ncbi.nlm.nih.gov/pubmed/30037795
http://dx.doi.org/10.1128/IAI.00360-18

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