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From 3D spheroids to tumor bearing mice: efficacy and distribution studies of trastuzumab-docetaxel immunoliposome in breast cancer

PURPOSE: Nanoparticles are of rising interest in cancer research, but in vitro canonical cell monolayer models are not suitable to evaluate their efficacy when prototyping candidates. Here, we developed three-dimensional (3D) spheroid models to test the efficacy of trastuzumab-docetaxel immunoliposo...

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Detalles Bibliográficos
Autores principales:	Rodallec, Anne, Sicard, Guillaume, Giacometti, Sarah, Carré, Manon, Pourroy, Bertrand, Bouquet, Fanny, Savina, Ariel, Lacarelle, Bruno, Ciccolini, Joseph, Fanciullino, Raphaelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204867/ https://www.ncbi.nlm.nih.gov/pubmed/30425482 http://dx.doi.org/10.2147/IJN.S179290

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