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Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease
INTRODUCTION: We investigated the effect of antihypertensive (aHTN) medications and cholinesterase inhibitors (ChEIs) on the cognitive decline in patients with Alzheimer's disease (AD) and analyzed synergism by chemogenomics systems pharmacology mapping. METHODS: We compared the effect of aHTN...
Autores principales: | Hu, Ziheng, Wang, Lirong, Ma, Shifan, Kirisci, Levent, Feng, Zhiwei, Xue, Ying, Klunk, William E., Kamboh, M. Ilyas, Sweet, Robert A., Becker, James, Lv, Qianzhou, Lopez, Oscar L., Xie, Xiang-Qun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205113/ https://www.ncbi.nlm.nih.gov/pubmed/30386819 http://dx.doi.org/10.1016/j.trci.2018.09.001 |
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