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lncRNA GAS5 Reverses EMT and Tumor Stem Cell-Mediated Gemcitabine Resistance and Metastasis by Targeting miR-221/SOCS3 in Pancreatic Cancer

Dysregulated long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) mediating chemotherapeutic drug effects and metastasis in pancreatic cancer (PC) are key reasons for the poor prognosis of this disease. lncRNA growth arrest-specific 5 (GAS5) is reported to be a tumor suppressor in multiple cancers....

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Detalles Bibliográficos
Autores principales:	Liu, Bingyan, Wu, Shaoqiu, Ma, Jun, Yan, Shuo, Xiao, Zhengguang, Wan, Linhuang, Zhang, Feng, Shang, Mingyi, Mao, Aiwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205337/ https://www.ncbi.nlm.nih.gov/pubmed/30388621 http://dx.doi.org/10.1016/j.omtn.2018.09.026

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