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Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes

Human bocavirus 1 (HBoV1), an autonomous parvovirus, is a helper virus supporting replication of wild-type adeno-associated virus 2 (AAV2). In this study, we compared the helper functions from HBoV1 with those from adenovirus (Ad) for the production of recombinant AAV (rAAV) vector in HEK293 cells....

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Detalles Bibliográficos
Autores principales:	Wang, Zekun, Cheng, Fang, Engelhardt, John F., Yan, Ziying, Qiu, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205362/ https://www.ncbi.nlm.nih.gov/pubmed/30397626 http://dx.doi.org/10.1016/j.omtm.2018.09.005

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