Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O(6)-methylguanine-DNA methyltransferase with a double arm hybrid molecule

Disordered expression of the epidermal growth factor receptor (EGFR) has been associated with induction of DNA repair genes (e.g. XRCC1, ERCC1) and resistance to radiation and genotoxic drugs. However, our previous work showed that EGFR inhibition did not affect O(6)-methylguanine-DNA methyltransfer...

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Detalles Bibliográficos
Autores principales: Rupp, Martin, Mouhri, Zhor Senhaji, Williams, Christopher, Jean-Claude, Bertrand J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205551/
https://www.ncbi.nlm.nih.gov/pubmed/30416678
http://dx.doi.org/10.18632/oncotarget.25120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205551/
https://www.ncbi.nlm.nih.gov/pubmed/30416678
http://dx.doi.org/10.18632/oncotarget.25120

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