Cargando…

Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survival

Ovarian cancer is the most lethal gynecological malignancy in the western world. Despite recent efforts to characterize ovarian cancer using molecular profiling, few targeted treatment options are currently available. Here, we examined genetic variants, fusion transcripts, SNP genotyping, and gene e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Engqvist, Hanna, Parris, Toshima Z., Rönnerman, Elisabeth Werner, Söderberg, Elin M.V., Biermann, Jana, Mateoiu, Claudia, Sundfeldt, Karin, Kovács, Anikó, Karlsson, Per, Helou, Khalil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205557/ https://www.ncbi.nlm.nih.gov/pubmed/30416686 http://dx.doi.org/10.18632/oncotarget.26225

Ejemplares similares

Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes
por: Engqvist, Hanna, et al.
Publicado: (2020)

Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry
por: Engqvist, Hanna, et al.
Publicado: (2020)

Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
por: Engqvist, Hanna, et al.
Publicado: (2019)

Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens
por: Larsson, Peter, et al.
Publicado: (2020)

Clonal relatedness in tumour pairs of breast cancer patients
por: Biermann, Jana, et al.
Publicado: (2018)

Genome-wide multi-omics profiling of the 8p11-p12 amplicon in breast carcinoma
por: Parris, Toshima Z., et al.
Publicado: (2018)

Pan-cancer analysis of genomic and transcriptomic data reveals the prognostic relevance of human proteasome genes in different cancer types
por: Larsson, Peter, et al.
Publicado: (2022)

Trefoil factor family proteins as potential diagnostic markers for mucinous invasive ovarian carcinoma
por: Werner Rönnerman, Elisabeth, et al.
Publicado: (2023)

The prognostic relevance of FOXA1 and Nestin expression in breast cancer metastases: a retrospective study of 164 cases during a 10-year period (2004–2014)
por: De Lara, Shahin, et al.
Publicado: (2019)

Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray
por: Möllerström, Elin, et al.
Publicado: (2010)

Previously diagnosed multiple primary malignancies in patients with breast carcinoma in Western Sweden between 2007 and 2018
por: Nyqvist, Jenny, et al.
Publicado: (2020)

Genetic alterations associated with multiple primary malignancies
por: Nyqvist, Jenny, et al.
Publicado: (2021)

Metachronous and Synchronous Occurrence of 5 Primary Malignancies in a Female Patient between 1997 and 2013: A Case Report with Germline and Somatic Genetic Analysis
por: Nyqvist, Jenny, et al.
Publicado: (2017)

Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome
por: Shubbar, Emman, et al.
Publicado: (2013)

Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma
por: Parris, Toshima Z, et al.
Publicado: (2014)

Male Breast Carcinoma after Irradiation and Long-Term Phenothiazine Exposure: A Case Report
por: Hultborn, Ragnar, et al.
Publicado: (2020)

Immunohistochemical evaluation of epithelial ovarian carcinomas identifies three different expression patterns of the MX35 antigen, NaPi2b
por: Levan, Kristina, et al.
Publicado: (2017)

Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts
por: Oparina, Nina, et al.
Publicado: (2021)

Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases
por: Janeva, Slavica, et al.
Publicado: (2023)

Distinct microRNA Expression Profiles in Mouse Renal Cortical Tissue after (177)Lu-octreotate Administration
por: Schüler, Emil, et al.
Publicado: (2014)

Clinical evaluation of molecular surrogate subtypes in patients with ipsilateral multifocal primary breast cancer
por: Janeva, Slavica, et al.
Publicado: (2023)

Effects of internal low-dose irradiation from (131)I on gene expression in normal tissues in Balb/c mice
por: Schüler, Emil, et al.
Publicado: (2011)

Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles
por: Rudqvist, Nils, et al.
Publicado: (2012)

Circadian rhythm influences genome-wide transcriptional responses to (131)I in a tissue-specific manner in mice
por: Langen, Britta, et al.
Publicado: (2015)

Pan-cancer analysis identifies BIRC5 as a prognostic biomarker
por: Fäldt Beding, Anna, et al.
Publicado: (2022)

Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors
por: Ciceri, Sara, et al.
Publicado: (2022)

Ovarian carcinoma histotype in Lynch syndrome
por: Gilks, C. Blake, et al.
Publicado: (2017)

Regulation of the viability of Nf1 deficient cells by PKC isoforms
por: Zhou, Xiaodong, et al.
Publicado: (2014)

Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors
por: Thomsson, Kristina A., et al.
Publicado: (2021)

Analysis of blood group antigens on MUC5AC in mucinous ovarian cancer tissues using in situ proximity ligation assay
por: Mateoiu, Constantina, et al.
Publicado: (2021)

Potential Biomarkers for Radiation-Induced Renal Toxicity following (177)Lu-Octreotate Administration in Mice
por: Schüler, Emil, et al.
Publicado: (2015)

Integrative Genomics with Mediation Analysis in a Survival Context
por: Nemes, Szilárd, et al.
Publicado: (2013)

Transcriptional Response in Mouse Thyroid Tissue after (211)At Administration: Effects of Absorbed Dose, Initial Dose-Rate and Time after Administration
por: Rudqvist, Nils, et al.
Publicado: (2015)

Transcriptional response in normal mouse tissues after i.v. (211)At administration - response related to absorbed dose, dose rate, and time
por: Langen, Britta, et al.
Publicado: (2015)

Gene expression signature in mouse thyroid tissue after (131)I and (211)At exposure
por: Rudqvist, Nils, et al.
Publicado: (2015)

Transcriptional response to (131)I exposure of rat thyroid gland
por: Rudqvist, Nils, et al.
Publicado: (2017)

Hedgehog inhibitor sonidegib potentiates (177)Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude mice
por: Spetz, Johan, et al.
Publicado: (2017)

Evaluation of Sialyl-Lactotetra as a Marker for Epithelial Ovarian Tumors
por: Barone, Angela, et al.
Publicado: (2020)

Mechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models
por: Huang, Yinglai, et al.
Publicado: (2018)

Age-related long-term response in rat thyroid tissue and plasma after internal low dose exposure to (131)I
por: Larsson, Malin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qim5bnl4l6n141r59pgeve68hb