Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia

In a large scale screen for skin, hair, and nail abnormalities in null mice generated by The Jackson Laboratory’s KOMP center, homozygous mutant Far2(tm2b(KOMP)Wtsi)/2J (hereafter referrred to as Far2(-/-)) mice were found to develop focal areas of alopecia as they aged. As sebocytes matured in wild...

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Detalles Bibliográficos
Autores principales: Sundberg, John P., Shen, Tong, Fiehn, Oliver, Rice, Robert H., Silva, Kathleen A., Kennedy, Victoria E., Gott, Nicholas E., Dionne, Louise A., Bechtold, Lesley S., Murray, Stephen A., Kuiper, Raoul, Pratt, C. Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205590/
https://www.ncbi.nlm.nih.gov/pubmed/30372477
http://dx.doi.org/10.1371/journal.pone.0205775

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