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Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns
The burgeoning literature on vitamin D deficiency and supplementation over the past decade or so has generated a greater understanding of some areas but also an appreciation of the many areas of equipoise. This is particularly relevant in the field of critical care with the heterogeneous patient pop...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205786/ https://www.ncbi.nlm.nih.gov/pubmed/30371341 http://dx.doi.org/10.1186/s13054-018-2185-8 |
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author | Nair, Priya Venkatesh, Balasubramaniam Center, Jacqueline R |
author_facet | Nair, Priya Venkatesh, Balasubramaniam Center, Jacqueline R |
author_sort | Nair, Priya |
collection | PubMed |
description | The burgeoning literature on vitamin D deficiency and supplementation over the past decade or so has generated a greater understanding of some areas but also an appreciation of the many areas of equipoise. This is particularly relevant in the field of critical care with the heterogeneous patient populations, the severity and duration of illness and the frequency of comorbid conditions. This review aims to summarise the current knowledge base of vitamin D deficiency within the context of critical illness—“the known knowns”—and also highlight the areas of recognised uncertainty—“the known unknowns”. It acknowledges the fact that there may well be other knowledge gaps of clinical relevance of which we are currently unaware—“the unknown unknowns”. |
format | Online Article Text |
id | pubmed-6205786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-62057862018-10-31 Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns Nair, Priya Venkatesh, Balasubramaniam Center, Jacqueline R Crit Care Review The burgeoning literature on vitamin D deficiency and supplementation over the past decade or so has generated a greater understanding of some areas but also an appreciation of the many areas of equipoise. This is particularly relevant in the field of critical care with the heterogeneous patient populations, the severity and duration of illness and the frequency of comorbid conditions. This review aims to summarise the current knowledge base of vitamin D deficiency within the context of critical illness—“the known knowns”—and also highlight the areas of recognised uncertainty—“the known unknowns”. It acknowledges the fact that there may well be other knowledge gaps of clinical relevance of which we are currently unaware—“the unknown unknowns”. BioMed Central 2018-10-29 /pmc/articles/PMC6205786/ /pubmed/30371341 http://dx.doi.org/10.1186/s13054-018-2185-8 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Nair, Priya Venkatesh, Balasubramaniam Center, Jacqueline R Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title | Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title_full | Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title_fullStr | Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title_full_unstemmed | Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title_short | Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns |
title_sort | vitamin d deficiency and supplementation in critical illness—the known knowns and known unknowns |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205786/ https://www.ncbi.nlm.nih.gov/pubmed/30371341 http://dx.doi.org/10.1186/s13054-018-2185-8 |
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