Cargando…

The Ca(2+) transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations

Conductances of ion channels and transporters controlling cardiac excitation may vary in a population of subjects with different cardiac gene expression patterns. However, the amount of variability and its origin are not quantitatively known. We propose a new conceptual approach to predict this vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Rees, Colin M, Yang, Jun-Hai, Santolini, Marc, Lusis, Aldons J, Weiss, James N, Karma, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205808/
https://www.ncbi.nlm.nih.gov/pubmed/30251624
http://dx.doi.org/10.7554/eLife.36717