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Engineering induction of singular neural rosette emergence within hPSC-derived tissues

Human pluripotent stem cell (hPSC)-derived neural organoids display unprecedented emergent properties. Yet in contrast to the singular neuroepithelial tube from which the entire central nervous system (CNS) develops in vivo, current organoid protocols yield tissues with multiple neuroepithelial unit...

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Detalles Bibliográficos
Autores principales:	Knight, Gavin T, Lundin, Brady F, Iyer, Nisha, Ashton, Lydia MT, Sethares, William A, Willett, Rebecca M, Ashton, Randolph Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205811/ https://www.ncbi.nlm.nih.gov/pubmed/30371350 http://dx.doi.org/10.7554/eLife.37549

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