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MCL-1 inhibition in cancer treatment

Myeloid cell leukemia-1 (MCL-1), a member of antiapoptotic BCL-2 family proteins, is a key regulator of mitochondrial homeostasis. Frequent overexpression of MCL-1 in human primary and drug-resistant cancer cells makes it an attractive cancer therapeutic target. Significant progress has been made in...

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Detalles Bibliográficos
Autores principales:	Xiang, Weiguo, Yang, Chao-Yie, Bai, Longchuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205821/ https://www.ncbi.nlm.nih.gov/pubmed/30425521 http://dx.doi.org/10.2147/OTT.S146228

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