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Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

Mitochondria fulfill vital metabolic functions and act as crucial cellular signaling hubs, integrating their metabolic status into the cellular context. Here, we show that defective cardiolipin remodeling, upon loss of the cardiolipin acyl transferase tafazzin, decreases HIF-1α signaling in hypoxia....

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Detalles Bibliográficos
Autores principales:	Chowdhury, Arpita, Aich, Abhishek, Jain, Gaurav, Wozny, Katharina, Lüchtenborg, Christian, Hartmann, Magnus, Bernhard, Olaf, Balleiniger, Martina, Alfar, Ezzaldin Ahmed, Zieseniss, Anke, Toischer, Karl, Guan, Kaomei, Rizzoli, Silvio O., Brügger, Britta, Fischer, Andrè, Katschinski, Dörthe M., Rehling, Peter, Dudek, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205837/ https://www.ncbi.nlm.nih.gov/pubmed/30332638 http://dx.doi.org/10.1016/j.celrep.2018.09.057

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