Cargando…

Mitochondrial dysfunction reduces the activity of KIR2.1 K(+) channel in myoblasts via impaired oxidative phosphorylation

Myoblast fusion depends on mitochondrial integrity and intracellular Ca(2+) signaling regulated by various ion channels. In this study, we investigated the ionic currents associated with [Ca(2+)](i) regulation in normal and mitochondrial DNA-depleted (ρ0) L6 myoblasts. The ρ0 myoblasts showed impair...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woo, JooHan, Kim, Hyun Jong, Nam, Yu Ran, Kim, Yung Kyu, Lee, Eun Ju, Choi, Inho, Kim, Sung Joon, Lee, Wan, Nam, Joo Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205933/ https://www.ncbi.nlm.nih.gov/pubmed/30402030 http://dx.doi.org/10.4196/kjpp.2018.22.6.697

Ejemplares similares

Cdo Regulates Surface Expression of Kir2.1 K(+) Channel in Myoblast Differentiation
por: Leem, Young-Eun, et al.
Publicado: (2016)

Gardenia jasminoides extract and its constituent, genipin, inhibit activation of CD3/CD28 co-stimulated CD4(+) T cells via ORAI1 channel
por: Kim, Hyun Jong, et al.
Publicado: (2020)

Human Myoblast Fusion Requires Expression of Functional Inward Rectifier Kir2.1 Channels
por: Fischer-Lougheed, Jacqueline, et al.
Publicado: (2001)

Cofilin Phosphorylation Decreased by Serum-free Starvation with Low Glucose in the L6 Myoblasts
por: Kim, Mee-Young, et al.
Publicado: (2014)

Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells
por: Kim, Hyun Jong, et al.
Publicado: (2020)

Transthyretin Is a Key Regulator of Myoblast Differentiation
por: Lee, Eun Ju, et al.
Publicado: (2013)

Secondary anionic phospholipid binding site and gating mechanism in Kir2.1 inward rectifier channels
por: Lee, Sun-Joo, et al.
Publicado: (2013)

Decrease of PKB/Akt Phosphorylation is Partially Mediated by SAPK/JNK Activation in Serum-free L6 Myoblasts Starved with Low Glucose
por: Kim, Mee-Young, et al.
Publicado: (2014)

Structural rearrangements underlying ligand-gating in Kir channels
por: Wang, Shizhen, et al.
Publicado: (2012)

Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone
por: Utrilla, Raquel G., et al.
Publicado: (2017)

Temperature-dependent increase in the calcium sensitivity and acceleration of activation of ANO6 chloride channel variants
por: Lin, Haiyue, et al.
Publicado: (2019)

Nitrite as Direct S-Nitrosylating Agent of Kir2.1 Channels
por: Montesanti, Gabriella, et al.
Publicado: (2014)

Mitochondrial oxidative phosphorylation complexes exist in the sarcolemma of skeletal muscle
por: Lee, Hyun, et al.
Publicado: (2016)

Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K(+) channels inhibition
por: Kim, Hyun Jong, et al.
Publicado: (2021)

The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels
por: Kurata, Harley T., et al.
Publicado: (2007)

ESCRT regulates surface expression of the Kir2.1 potassium channel
por: Kolb, Alexander R., et al.
Publicado: (2014)

Linkage analysis reveals allosteric coupling in Kir2.1 channels
por: Sigg, Daniel M., et al.
Publicado: (2018)

Seeing spermine blocking of K(+) ion movement through inward rectifier Kir2.2 channels
por: Lee, Sun-Joo, et al.
Publicado: (2022)

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism–epilepsy phenotype
por: Ambrosini, Elena, et al.
Publicado: (2014)

Inwardly Rectifying Potassium Channel Kir2.1 and its “Kir-ious” Regulation by Protein Trafficking and Roles in Development and Disease
por: Hager, Natalie A., et al.
Publicado: (2022)

Effects of corticotropin-releasing hormone on the expression of adenosine triphosphate-sensitive potassium channels (Kir6.1/SUR2B) in human term pregnant myometrium
por: Kim, Joo Young, et al.
Publicado: (2018)

Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway
por: Park, Cheol, et al.
Publicado: (2019)

Block of the Kir2.1 Channel Pore by Alkylamine Analogues of Endogenous Polyamines
por: Pearson, W.L., et al.
Publicado: (1998)

Subunit gating resulting from individual protonation events in Kir2 channels
por: Maksaev, Grigory, et al.
Publicado: (2023)

Subunit gating resulting from individual protonation events in Kir2 channels
por: Maksaev, Grigory, et al.
Publicado: (2023)

Dysfunction of Mitochondrial Dynamics in Drosophila Model of Diabetic Nephropathy
por: Kim, Kiyoung, et al.
Publicado: (2021)

Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1
por: Lee, Jong-Kook, et al.
Publicado: (1999)

Irisin promotes C2C12 myoblast proliferation via ERK-dependent CCL7 upregulation
por: Lee, Jangho, et al.
Publicado: (2019)

Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition
por: Hong, Phan Thi Lam, et al.
Publicado: (2021)

Functional consequences of Kir2.1/Kir2.2 subunit heteromerization
por: Panama, Brian K., et al.
Publicado: (2010)

Electrostatics in the Cytoplasmic Pore Produce Intrinsic Inward Rectification in Kir2.1 Channels
por: Yeh, Shih-Hao, et al.
Publicado: (2005)

Modulation of Actin Filament Dynamics by Inward Rectifying of Potassium Channel Kir2.1
por: Wu, Lida, et al.
Publicado: (2020)

Sildenafil affects the human Kir2.1 and Kir2.2 channels at clinically relevant concentrations: Inhibition potentiated by low Ba(2+)
por: Iijima, Akimasa, et al.
Publicado: (2023)

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids
por: Lee, Sun-Joo, et al.
Publicado: (2016)

Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology
por: Kim, Sung Eun, et al.
Publicado: (2023)

Activation of transient receptor potential vanilloid 3 by the methanolic extract of Schisandra chinensis fruit and its chemical constituent γ-schisandrin
por: Nam, Yuran, et al.
Publicado: (2017)

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels
por: Zangerl-Plessl, Eva-Maria, et al.
Publicado: (2019)

Permeant Ion-Dependent Changes in Gating of Kir2.1 Inward Rectifier Potassium Channels
por: Lu, Tao, et al.
Publicado: (2001)

Characterization of the chicken inward rectifier K(+ )channel IRK1/Kir2.1 gene
por: Mutai, Hideki, et al.
Publicado: (2004)

Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels
por: Chang, Hsueh-Kai, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_oie1u9gcmmh61ve880dq8svso7