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Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating kinase P...

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Detalles Bibliográficos
Autores principales: Hashi, Kana, Imai, Chihiro, Yahara, Koji, Tahmina, Kamrunnesa, Hayashi, Takeru, Azuma, Takeshi, Miyabe-Nishiwaki, Takako, Sato, Hideyuki, Matsuoka, Masao, Niimi, Sachi, Okamoto, Munehiro, Hatakeyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206097/
https://www.ncbi.nlm.nih.gov/pubmed/30374120
http://dx.doi.org/10.1038/s41598-018-34425-4