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Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate
Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating kinase P...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206097/ https://www.ncbi.nlm.nih.gov/pubmed/30374120 http://dx.doi.org/10.1038/s41598-018-34425-4 |