Cargando…

Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate

Helicobacter pylori cagA-positive strains are critically involved in the development of gastric cancer. Upon delivery into gastric epithelial cells via type IV secretion, the cagA-encoded CagA interacts with and thereby perturbs the pro-oncogenic phosphatase SHP2 and the polarity-regulating kinase P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hashi, Kana, Imai, Chihiro, Yahara, Koji, Tahmina, Kamrunnesa, Hayashi, Takeru, Azuma, Takeshi, Miyabe-Nishiwaki, Takako, Sato, Hideyuki, Matsuoka, Masao, Niimi, Sachi, Okamoto, Munehiro, Hatakeyama, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206097/ https://www.ncbi.nlm.nih.gov/pubmed/30374120 http://dx.doi.org/10.1038/s41598-018-34425-4

Ejemplares similares

Evolution of cagA Oncogene of Helicobacter pylori through Recombination
por: Furuta, Yoshikazu, et al.
Publicado: (2011)

Natural variant of the Helicobacter pylori CagA oncoprotein that lost the ability to interact with PAR1
por: Hashi, Kana, et al.
Publicado: (2014)

Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA
por: Shimoda, Asako, et al.
Publicado: (2016)

Impact of structural polymorphism for the Helicobacter pylori CagA oncoprotein on binding to polarity-regulating kinase PAR1b
por: Nishikawa, Hiroko, et al.
Publicado: (2016)

Mixed Infection with cagA Positive and cagA Negative Strains of Helicobacter pylori Lowers Disease Burden in The Gambia
por: Secka, Ousman, et al.
Publicado: (2011)

Dramatic increase in SHP2 binding activity of Helicobacter pylori Western CagA by EPIYA-C duplication: its implications in gastric carcinogenesis
por: Nagase, Lisa, et al.
Publicado: (2015)

Characterizing Helicobacter pylori cagA in Myanmar
por: Myint, Thein, et al.
Publicado: (2018)

Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein
por: Suzuki, Nobumi, et al.
Publicado: (2015)

Cag Type IV Secretion System: CagI Independent Bacterial Surface Localization of CagA
por: Kumar, Navin, et al.
Publicado: (2013)

Molecular anatomy and pathogenic actions of Helicobacter pylori CagA that underpin gastric carcinogenesis
por: Takahashi-Kanemitsu, Atsushi, et al.
Publicado: (2019)

Mouse Gastric Epithelial Cells Resist CagA Delivery by the Helicobacter pylori Type IV Secretion System
por: Shrestha, Rejina, et al.
Publicado: (2022)

CagA(+) Helicobacter pylori, Not CagA(–) Helicobacter pylori, Infection Impairs Endothelial Function Through Exosomes-Mediated ROS Formation
por: Xia, Xiujuan, et al.
Publicado: (2022)

Role of CagA in H. pylori gastric cancer
Publicado: (2013)

EPIYA motiefs of cagA and upper gastrointestinal diseases
por: Soleiman-Meigooni, Saeed, et al.
Publicado: (2015)

Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer
por: HATAKEYAMA, Masanori
Publicado: (2017)

Sequence Polymorphism and Intrinsic Structural Disorder as Related to Pathobiological Performance of the Helicobacter pylori CagA Oncoprotein
por: Nishikawa, Hiroko, et al.
Publicado: (2017)

Conformational Analysis of Isolated Domains of Helicobacter pylori CagA
por: Woon, Amanda P., et al.
Publicado: (2013)

Evaluating the relationship between serum immunoglobulin G (IgG) and A (IgA) anti-CagA antibody and the cagA gene in patients with dyspepsia
por: Fakhre-Yaseri, Hashem, et al.
Publicado: (2017)

An RGD Helper Sequence in CagL of Helicobacter pylori Assists in Interactions with Integrins and Injection of CagA
por: Conradi, Jens, et al.
Publicado: (2012)

Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells
por: Fujii, Yumiko, et al.
Publicado: (2020)

Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila
por: Reid, David W., et al.
Publicado: (2012)

Helicobacter pylori cagA gene variants in Malaysians of different ethnicity
por: Mohamed, Ramelah, et al.
Publicado: (2009)

Fragmentation of CagA Reduces Hummingbird Phenotype Induction by Helicobactor pylori
por: Chang, Chih-Chi, et al.
Publicado: (2016)

Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation
por: Zhao, Qing, et al.
Publicado: (2018)

Evolutionary mechanism leading to the multi-cagA genotype in Helicobacter pylori
por: Su, Hanfu, et al.
Publicado: (2019)

Influence of Dietary Factors on Helicobacter pylori and CagA Seroprevalence in Bulgaria
por: Yordanov, Daniel, et al.
Publicado: (2017)

Construction, Cloning, and Expression of CagA Recombinant Protein of Helicobacter pylori
por: Shapouri Moghaddam, Abbas, et al.
Publicado: (2020)

Functional antagonism between CagA and DLC1 in gastric cancer
por: Hinsenkamp, Isabel, et al.
Publicado: (2022)

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer
por: Roy, Rony K., et al.
Publicado: (2016)

Helicobacter pylori Infection in Thailand: A Nationwide Study of the CagA Phenotype
por: Uchida, Tomohisa, et al.
Publicado: (2015)

The Role of H. pylori CagA in Regulating Hormones of Functional Dyspepsia Patients
por: Meng, Wang-Ping, et al.
Publicado: (2016)

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients
por: Archampong, Timothy N., et al.
Publicado: (2017)

Interaction of CagA with Crk plays an important role in Helicobacter pylori–induced loss of gastric epithelial cell adhesion
por: Suzuki, Masato, et al.
Publicado: (2005)

Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21
por: Saito, Yasuhiro, et al.
Publicado: (2010)

Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori
por: Backert, Steffen, et al.
Publicado: (2011)

Helicobacter pylori CagA Disrupts Epithelial Patterning by Activating Myosin Light Chain
por: Muyskens, Jonathan B., et al.
Publicado: (2011)

Inhibitory Effects of Anthocyanins on Secretion of Helicobacter pylori CagA and VacA Toxins
por: Kim, Sa-Hyun, et al.
Publicado: (2012)

Clinical relevance of the cagA, tnpA and tnpB genes in Helicobacter pylori
por: Abadi, Amin Talebi Bezmin, et al.
Publicado: (2014)

The CagA toxin of Helicobacter pylori: abundant production but relatively low amount translocated
por: Jiménez-Soto, Luisa F., et al.
Publicado: (2016)

Influence of H. pylori CagA Coupled with Alcohol Consumption on Cytokine Profiles in Men
por: Qu, Baoge, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6u4jq6gpa1eh4034ftvnm2ajsk