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Reversal of cerebrovascular constriction in experimental cerebral malaria by L-arginine

Vascular dysfunction associated with low nitric oxide (NO) biavailability and low plasma L-arginine levels is observed in both human and experimental cerebral malaria (ECM). In ECM, cerebrovascular constriction results in decreased pial blood flow and hypoxia, and administration of NO donors reverse...

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Detalles Bibliográficos
Autores principales: Ong, Peng Kai, Moreira, Aline S., Daniel-Ribeiro, Cláudio T., Frangos, John A., Carvalho, Leonardo J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206133/
https://www.ncbi.nlm.nih.gov/pubmed/30374028
http://dx.doi.org/10.1038/s41598-018-34249-2