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Reversal of cerebrovascular constriction in experimental cerebral malaria by L-arginine
Vascular dysfunction associated with low nitric oxide (NO) biavailability and low plasma L-arginine levels is observed in both human and experimental cerebral malaria (ECM). In ECM, cerebrovascular constriction results in decreased pial blood flow and hypoxia, and administration of NO donors reverse...
Autores principales: | Ong, Peng Kai, Moreira, Aline S., Daniel-Ribeiro, Cláudio T., Frangos, John A., Carvalho, Leonardo J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206133/ https://www.ncbi.nlm.nih.gov/pubmed/30374028 http://dx.doi.org/10.1038/s41598-018-34249-2 |
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