Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism

Secreted FGF binding proteins (FGFBP) mobilize locally-acting paracrine FGFs from their extracellular storage. Here, we report that FGFBP3 (BP3) modulates fat and glucose metabolism in mouse models of metabolic syndrome. BP3 knockout mice exhibited altered lipid metabolism pathways with reduced hepa...

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Detalles Bibliográficos
Autores principales: Tassi, Elena, Garman, Khalid A., Schmidt, Marcel O., Ma, Xiaoting, Kabbara, Khaled W., Uren, Aykut, Tomita, York, Goetz, Regina, Mohammadi, Moosa, Wilcox, Christopher S., Riegel, Anna T., Carlstrom, Mattias, Wellstein, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206164/
https://www.ncbi.nlm.nih.gov/pubmed/30374109
http://dx.doi.org/10.1038/s41598-018-34238-5

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