The Antitumor Activities of Marsdenia tenacissima

Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activat...

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Autores principales: Wang, Xiang, Yan, Yuanliang, Chen, Xi, Zeng, Shuangshuang, Qian, Long, Ren, Xinxin, Wei, Jie, Yang, Xue, Zhou, Yangying, Gong, Zhicheng, Xu, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206208/
https://www.ncbi.nlm.nih.gov/pubmed/30406035
http://dx.doi.org/10.3389/fonc.2018.00473
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author Wang, Xiang
Yan, Yuanliang
Chen, Xi
Zeng, Shuangshuang
Qian, Long
Ren, Xinxin
Wei, Jie
Yang, Xue
Zhou, Yangying
Gong, Zhicheng
Xu, Zhijie
author_facet Wang, Xiang
Yan, Yuanliang
Chen, Xi
Zeng, Shuangshuang
Qian, Long
Ren, Xinxin
Wei, Jie
Yang, Xue
Zhou, Yangying
Gong, Zhicheng
Xu, Zhijie
author_sort Wang, Xiang
collection PubMed
description Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization.
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spelling pubmed-62062082018-11-07 The Antitumor Activities of Marsdenia tenacissima Wang, Xiang Yan, Yuanliang Chen, Xi Zeng, Shuangshuang Qian, Long Ren, Xinxin Wei, Jie Yang, Xue Zhou, Yangying Gong, Zhicheng Xu, Zhijie Front Oncol Oncology Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization. Frontiers Media S.A. 2018-10-23 /pmc/articles/PMC6206208/ /pubmed/30406035 http://dx.doi.org/10.3389/fonc.2018.00473 Text en Copyright © 2018 Wang, Yan, Chen, Zeng, Qian, Ren, Wei, Yang, Zhou, Gong and Xu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wang, Xiang
Yan, Yuanliang
Chen, Xi
Zeng, Shuangshuang
Qian, Long
Ren, Xinxin
Wei, Jie
Yang, Xue
Zhou, Yangying
Gong, Zhicheng
Xu, Zhijie
The Antitumor Activities of Marsdenia tenacissima
title The Antitumor Activities of Marsdenia tenacissima
title_full The Antitumor Activities of Marsdenia tenacissima
title_fullStr The Antitumor Activities of Marsdenia tenacissima
title_full_unstemmed The Antitumor Activities of Marsdenia tenacissima
title_short The Antitumor Activities of Marsdenia tenacissima
title_sort antitumor activities of marsdenia tenacissima
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206208/
https://www.ncbi.nlm.nih.gov/pubmed/30406035
http://dx.doi.org/10.3389/fonc.2018.00473
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