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Overexpression of Kcnmb2 in Dorsal CA1 of Offspring Mice Rescues Hippocampal Dysfunction Caused by a Methyl Donor-Rich Paternal Diet

BK channels are known regulators of neuronal excitability, synaptic plasticity, and memory. Our previous study showed that a paternal methyl donor-rich diet reduced the expression of Kcnmb2, which encodes BK channel subunit beta 2, and caused memory deficits in offspring mice. To explore the underly...

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Detalles Bibliográficos
Autores principales: Yu, Ming, Guo, Li, Li, Nan, Henzel, Kristin S., Gu, Huating, Ran, Xiufang, Sun, Wei, Liu, Shuai, Lu, Yingchang, Ehninger, Dan, Zhou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206260/
https://www.ncbi.nlm.nih.gov/pubmed/30405352
http://dx.doi.org/10.3389/fncel.2018.00360

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