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Marek’s Disease Virus Activates the PI3K/Akt Pathway Through Interaction of Its Protein Meq With the P85 Subunit of PI3K to Promote Viral Replication

It is known that viruses can active the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in host cells to support cell survival and viral replication; however, the role of PI3K/Akt signaling in the pathogenic mechanisms induced by Marek’s disease virus (MDV) which causes a neoplastic Marek...

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Detalles Bibliográficos
Autores principales: Li, Huimin, Zhu, Jiaojiao, He, Minyi, Luo, Qiong, Liu, Fan, Chen, Ruiai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206265/
https://www.ncbi.nlm.nih.gov/pubmed/30405592
http://dx.doi.org/10.3389/fmicb.2018.02547