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Difference in morphology and interactome profiles between orthotopic and subcutaneous gastric cancer xenograft models

In xenograft models, orthotopic (ORT) engraftment is thought to provide a different tumor microenvironment compared with subcutaneous (SC) engraftment. We attempted to characterize the biological difference between OE19 (adenocarcinoma of the gastroesophageal junction) SC and ORT models by pathologi...

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Detalles Bibliográficos
Autores principales: Nakano, Kiyotaka, Nishizawa, Takashi, Komura, Daisuke, Fujii, Etsuko, Monnai, Makoto, Kato, Atsuhiko, Funahashi, Shin-ichi, Ishikawa, Shumpei, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206286/
https://www.ncbi.nlm.nih.gov/pubmed/30393433
http://dx.doi.org/10.1293/tox.2018-0020